Longvida® Safety

Longvida® has been self-affirmed GRAS since 2012 and has been extensively investigated for its efficacy and safety in multiple human clinical trials, animal studies, and in in vitro experimental studies.


Gota et al (2010) investigated the pharmacokinetics of Longvida® compared to 95% standard curcuminoids in a crossover, double-blind, comparative pharmacokinetic analysis in healthy adult human subjects. In these healthy subjects, the mean peak concentration of curcumin (Cmax) achieved from dosing 650mg of Longvida® SLCP was 22.43 ng/mL, whereas plasma curcumin from dosing an equal quantity of unformulated 95% curcuminoids extract was not detected (<1 ng/ml). In the same study, administration of Longvida® in oral dosages of 2000mg, 3000mg, and 4000mg (containing 400-600mg of curcumin, respectively), with 8oz of water to osteosarcoma patients showed high plasma concentrations and dose-related AUCs. Overall, good tolerability was noted in both healthy and osteosarcoma groups.

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OptiMSM® and Suphur: Nature's Beauty Mineral

MSM (methylsulfonylmethane) is a rich source of sulphur (34% by weight) and a key component of collagen that supports the skin’s structural framework. It is also a building block of keratin, the main structural constituent of hair and nails.

 In recent years, Bergstrom Nutrition, the manufacturers of OptiMSM® has employed the most cutting-edge technology to research how OptiMSM® works to support healthy, younger skin. Findings have demonstrated that OptiMSM® may reduce fine lines and wrinkles, improve skin texture and elasticity and provide overall support to the structural integrity of the skin. Furthermore OptiMSM® benefits may also help the skin, hair and nails to regain and retain a more youthful appearance, with only 1 gram daily (study awaiting for publication). A brief overview of the finding of this recent reseach can be downloaded here.

OptiMSM® is a USA made, 99.9% pure, consistent and high-quality form of MSM, backed by extensive scientific and toxicological data and more than 30 years’ experience. To learn more, please visit our dedicated page or contact us.

EpiCor® + Probiotics: Discover our proposal for Immune & Gut health

Thanks to our partnership with Embria Health Sciences, the manufacturers of EpiCor®, and Probiotical S.p.A. in Italy, we have developed a product formulation containing three scientifically proven ingredients for immune and gut health: EpiCor®, Bifidobacterium animalis subsp. lactis BS01 and Lactobacillus rhamnosus LR04. The formula also includes  fructooligosaccharides (FOS), a well-researched prebiotic. 

EpiCor® is a clinically researched fermentate shown to support the immune system and gut for better overall health. More information about this ingredient and scientific research behind can be found in our EpiCor® dedicated page, providing you are logged as a registered website user. 

Download here our new EpiCor & Probiotical product profile sheet. Discover what we have on offer on Immune and Gut Health by watching our Immune Health Product Video and Gut Health Product Video

Contact us to receive more information. 

Product Highlight: Ester-C®

Ester-C® Calcium Ascorbate -Threonate was discovered back in the early 80s, when its inventor, an ever-curious doctor and scientist set out on a quest for the first stomach-friendly Vitamin. The result of his research is what we know today as Ester-C®, a unique form of Vitamin C.

Clinical studies show that Ester-C® increases vitamin C levels in white blood cells, which are essential part of the immune system. Ester-C® stays in the body longer than regular vitamin C, up to 24 hours. The naturally occurring metabolites in the formula are the reason why it lasts longer than generic Vitamin C. Ester-C® has neutral pH, therefore designed to be non-acidic so it can be taken all year long and in a variety of application and formats. All the EFSA Claims for Vitamin C can be used for Ester-C®, with the benefits and advantages of this patented ingredient.

To download all the clinical studies and learn more, please visit our dedicated  Ester-C® page or contact us. Please remember to login as a registered customer before accessing the page.

Click here to watch our  video on Immune Health.

Discover the Benefits of Thylakoids for Appetite Control

A recent study showed that the reduction in hedonic hunger, which we often refer to as craving sugar and unhealthy foods, is a particularly strong effect of thylakoids: the main active compound found in Appethyl®.

 Appethyl® is made 100% from spinach, which is carefully processed to preserve all its benefits and in particular thylakoids.

Appethyl® has been clinically-tested to show numerous benefits including significant reduction of hunger and cravings by slowing down digestion.  

To learn more, please visit the Appethyl® dedicated page in our website. Please remember to login as a registered user before accessing the page.

Longvida®: New Study

“Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study” is the title of the latest publication about Longvida® in the Journal of Inflammation Research.

The independent double-blind, placebo-controlled, human clinical trial demonstrated that oral administration of Longvida® (400mg twice a day) was found to be effective and safe in alleviating symptoms in patients suffering from knee osteoarthritis when administered for 90 days. This improvement was comparable to sub-therapeutic doses of ibuprofen. Significant improvements in VAS and WOMAC scores compared to baseline were observed. Longvida® was found to be “faster acting” in providing “pain relief” compared to ibuprofen in the first 30 days. No serious adverse events were reported, therefore this study further confirms the safety of Longvida®.

 For more information, download the full version of the study here. Please make sure you are logged as a registered user before accessing the product page.

Add Omega-3 in your Tablet: New GOtab Grades Available

LEHVOSS Nutrition can now offer GOtab 120/90 and GOtab 30/150 in addition to GOtab90/60. Download here the new product profile sheet for more details on all three grades and visit our dedicated GOtab page to download the specifications.

 Including high amounts of oil into a powder, to be compressed into a tablet, is challenging.  Thanks to the OmegaTri™ technology, Golden Omega fish oil concentrates can be included in tablets, offering scientifically proven benefits and excellent stability.

Explore new formulation opportunities such us Omega-3 + Zinc, Omega-3+Glucosamine, Omega3 + Folic Acid, Omega3 + Lutein/Carotenoids, Omega-3 + B Vitamins, and more. Contact us.

Longvida® winner of “Nutrition Research Project of the Year”

We are pleased to announce that Longvida® has received recognition by winning NutraIngredients-USA Award “Nutrition Research Project of the Year” for their research “Longvida’s Retinal Amyloid Pathology and Proof-of-Concept Imaging Clinical Trial with Longvida Optimized Curcumin”. This category rewards the most innovative and impactful nutrition research projects pushing the boundaries of nutritional science.

 When presenting the award, Dr. Stephen Daniells, PhD, Editor-in-Chief of NutraIngredients-USA explained on the behalf of the judges that the “entry really stood out for its combination of a nutrition intervention (curcumin) with industry-changing technology to potentially provide a low-cost, non-invasive technique to pre-screen at-risk populations using high-resolution imaging of a person’s amyloid-beta burden.” He went on to explain that the panel of judges appreciated that “the research was performed by an impressive team of academic institutions and industry, supported by peer-reviewed publications”.

 Visit our Longvida download area to have access to the full version of this scientific research. Please remember to login as a registered user before loading the page.

 Longvida® contains the natural antioxidant curcumin, optimized by SLCP™ technology for maximum bioavailability into blood and target tissues. It supplies significant levels of free (not glucuronidated or inactivated) curcumin.

Contact us for more information. 

Bacognize® & Sleep Support

Clinical research indicates that Bacognize® may offer a broad array of benefits for cognitive health linked to major neuroprotective mechanisms including neurotransmitter receptor (serotonin) binding activity. This is thanks to its natural spectrum standardization to specific bacopa glycosides, tested and confirmed for serotonin receptor activity.Bacognize® has 3 human clinical studies and 3 preclinical studies for memory, mood, and focus and can be used in daily life or specifically in sports to help focus without using stimulants.  Clinical research is available from our Bacognize® dedicated page.

Furthermore, research suggests that proprietary Bacognize® extract may help to both promote better quality of sleep and support the regulation of sleep cycles by interacting with serotonin receptors, helping to alleviate stress, and providing antioxidation benefits.

Learn more by reading the new White Paper "Bacognize® & Sleep Support" available in the Bacognize® download area.

Contact us for more information.

Discover HAPLEX®Plus

HAPLEX®Plus is a high purity, scientifically proven, food grade Sodium Hyaluronate. The ingredient it is manufactured by Bloomage Freda, the largest Sodium Hyaluronate manufacturer in the world, with more than 20 years’ experience.

Clinical research on HAPLEX®Plus shows improvements in skin elasticity, degenerative osteoarthritis and osteoporosis. HAPLEX®Plus is available in two versions, low molecular and high molecular weight.

Download here the HAPLEX®Plus White Paper to learn more.

HAPLEX®Plus is part of the Gee Lawson range of branded ingredients, available in all Europe (except for Spain) from LEHVOSS Nutrition. Cosmetic grade is also available through our Personal Care division.